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In the current study, using data from the DASH–Sodium trial, during screening when participants are consuming their normal dietary intake, we report a slope increment of an elevation in SBP of approximately 3 mmHg across the urinary Na + excretion range of 2–5 g/day in SS, but not SR participants. However, when assessed across the full range of observed urinary Na + excretion values we did not observe a positive correlation between SBP and urinary Na + excretion in either SS or SR participants. Significantly, despite urinary K + excretion of <1 g K + /day associating with higher SBP in SS and SR participants further increments in urinary K + excretion did not correlate with a reduction in SBP in either participant group. Furthermore, at baseline screening we did not observe a correlation between the urinary Na + :K + excretion ratio irrespective of the salt sensitivity of blood pressure. As such our data, from the DASH–Sodium Trial, in US participants at both baseline screening and following a highly controlled dietary intervention does not support the hypothesis that a reduced urinary Na + :K + ratio will be beneficial in population level blood pressure reduction or support the proposal for a urinary Na + :K + molar ratio of <1 to lower blood pressure.
After the Dash dieting intervention we seen no relationship ranging from a beneficial urinary Na + :K + proportion and you may SBP either in SS or SR participants
Compared with this new Natural , INTERSALT , and you will INTERMAP training, one to based a people peak confident connection between urinary Na + removal and you can blood circulation pressure, the brand new Dash–Salt Trial permits the organization of one’s salt awareness out-of bloodstream stress during the demonstration participants. Continue reading “Inside the SR professionals i observed zero relationships anywhere between urinary Na + removal and you will SBP”