We found that subsequent duct tube elongation additionally requires AFF-1. In aff-1 mutants, the duct cellular features a tremendously quick techniques, in addition to lumen is only a third of its regular duration (Fig. 2). Both phenotypes is rescued by aff-1pro::AFF-1 (Fig. 2). The aff-1 quick duct phenotype was epistatic to let-60 ras(gf) (Fig. 2), in keeping with AFF-1 acting downstream of Ras signaling. Continue reading “AFF-1 is needed for duct tubing elongation and apically guided trafficking”
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