Dialogue
Blood clots is because of bloodstream solidification and you may unpredictable viscosity on account of obstacles affecting their fluidity; it contributes to the synthesis of thrombocytes and you may activation out-of bloodstream coagulation factor (8–10). Therefore, repairing blood viscosity and you may improving blood coagulation function indexes has actually a keen essential part throughout the protection and you can remedy for DVT.
The investigation showed that having three days and you will ten weeks shortly after DVT modeling, hemorheology and you will coagulation indexes was in fact a knowledgeable about high-serving folic acidic and you may nutritional B12 category. Some account has recommended one to Hcy try a beneficial blood clots-building broker, and higher Hcy you may induce strong venous thrombosis (14–17). Additionally, plasma D-dimer could have been proposed having an excellent forewarning mode getting thrombus and you can hypercoagulable state (18,19). Ten weeks just after DVT acting, i discovered that the levels out of Hcy and you may D-dimer increased one particular on the high-serving group.
Because of histopathologic examination, we discovered that ten days once DVT modeling the fresh higher-serving and you may reduced-serving communities showed extreme improvement in the change from lower extremity strong venous thrombosis. Strong venous thrombosis off lower extremity having colour Doppler ultrasound prognosis has some pros, such as for instance effortless operation, cover and you can high efficiency, discount, repeatability and you will direct observation, additionally the identification out of related lesions and you may bleeding have to blood vessels (20). Our show along with indicated that shortly after DVT modeling, the newest effective price off all the way down extremity strong venous thrombosis treatments for high-serving classification is actually a hundred%. The outcomes of colour Doppler ultrasound prognosis from DVT corresponded so you’re able to the results for the histopathologic test. That it validated the fresh feasibility and you may energy saving regarding colour Doppler ultrasound prognosis to have deep venous thrombosis of the lower extremity.
Inside sumin B12 enjoys clear healing outcomes when you look at the a rabbit design of DVT having hyperhomocysteinemia. The newest large-doses i attempted improved individuals relevant periods, such as the levels of Hcy and you may D-dimer, hemorheology, coagulation mode, and you can vein cystic. Complete, these studies hold the access to high dosages from folic acidic and you can vitamin B12 to alleviate DVT.
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